Genes and enzymes

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چکیده

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The phase I cytochrome P450 (CYP) isoenzymes have received substantial attention in the pharmacogenetic literature. Researchers are beginning to examine the role of the phase II UDP-glucuronosyltransferase (UGT) enzymes, which produce products that are more water-soluble, less toxic and more readily excreted than the parent compounds. Several reasons may have contributed to neglect of UGTs (com...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1976

ISSN: 0014-5793

DOI: 10.1016/0014-5793(76)80852-6